The_Info_Web/30 - PROGRAMS & PROJECTS/HISTORICAL_PROGRAMS/MKSEARCH.md

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---
category: "Intelligence Operation"
tags:
- Program
- CIA
- MKULTRA
- BehavioralControl
- ColdWar
summary: "The CIA behavioral control program that succeeded MKULTRA in 1964 under Richard Helms, retaining the most sensitive chemical and biological development activities until Gottlieb terminated it in June 1972."
location: Washington, D.C.
relations:
- type: participant_in
with: "[[Office of Naval Research]]"
start: 1971-02-26
end: 1972-06-23
role: "Navy conduit for up to 117,938 dollars of CIA funds to a Massachusetts contractor, in part under the OFTEN label"
fn: 2
- type: participant_in
with: "[[Edgewood Arsenal]]"
start: 1967
end: 1973
role: "Edgewood Arsenal Research Laboratories took part in the MKCHICKWIT and MKOFTEN work, including testing of the compound EA 3167"
fn: 2
created: 2026-06-03
updated: 2026-10-15
---
MKSEARCH was the [[CIA]] program that succeeded [[MKULTRA]] in June 1964, when [[Richard Helms]] agreed to a new charter on the condition that it be almost the same as the old one. He kept the approval process within his control and made sure files would remain inside [[TSS]]. [[Sidney Gottlieb|Sid Gottlieb]] regrouped the most sensitive behavioral activities under the MKSEARCH umbrella, pruning away programs of insufficient sensitivity and turning exotic research over to the Science Directorate. He chose to continue seven projects, emphasizing chemical and biological substances valued for their ability to disorient, discredit, injure, or kill.[^1]
### The Seven Subprojects
First was the safehouse program for drug testing run by [[George White]] and others in the [[Federal Bureau of Narcotics]]. Even in 1964, Gottlieb and Helms had not given up hope that unwitting experiments could be resumed, paying $30,000 that year to keep the safehouses open. The [[San Francisco]] operation stayed active until June 1965, and the New York safehouse until the following year. Second was a $150,000-a-year contract with a Baltimore biological laboratory that gave [[Office of Technical Service|TSS]] "quick-delivery capability" for large-scale production of microorganisms, a private alternative to [[Fort Detrick]] that kept the Army from knowing what the CIA was producing. Third was Dr. James Hamilton, the San Francisco psychiatrist who arranged access to prisoners at the California Medical Facility at Vacaville for clinical testing of "behavioral control materials." In a six-month span in 1967 and 1968, he spent over $10,000 in CIA funds on between 400 and 1,000 inmates.[^1]
Fourth was a prominent industrialist who custom-manufactured rare chemicals, supplying the Agency with 3 kilos of a deadly carbamate in 1960, the same poison [[Stanley Lovell|OSS's Stanley Lovell]] had tried to use against Hitler. Fifth was Dr. [[Maitland Baldwin]], the brain surgeon who performed lobotomies on apes, put them in sensory deprivation, and beamed radio frequency energy directly at chimpanzee brains. Sixth was Dr. Charles Geschickter, who tested powerful drugs on mental defectives and terminal cancer patients at Georgetown University Hospital and whose family foundation channeled $2.1 million to other researchers. Seventh was Dr. Carl Pfeiffer, who tested drugs on inmates of the Federal penitentiary in [[Atlanta]] and the Bordentown reformatory, and sat on the FDA committee that allocated [[LSD]] for scientific research.[^1]
### Dissolution
MKSEARCH continued through the 1960s with a steadily decreasing budget: $250,000 in 1964, down to $110,000 and four subprojects in 1972. In June 1972, Gottlieb decided to end it, writing: "It has become very clear that these materials and techniques are too unpredictable in their effect on individual human beings, under specific circumstances, to be operationally useful. Our operations officers, particularly the emerging group of new senior operations officers, have shown a discerning and perhaps commendable distaste for utilizing these materials and techniques." He noted moral and ethical considerations and the extreme sensitivity and security constraints that effectively ruled out such operations.[^1]
Before retiring, Gottlieb and Helms mutually agreed to destroy all documentary traces of [[Project MKUltra|MKULTRA]]. Seven boxes of substantive records were incinerated, but seven more containing invoices and financial records survived due to misfiling. These surviving records eventually formed the basis for public revelations about the programs.[^1]
### Department of Defense search, 1977
In a memorandum for the Secretary of Defense dated September 20, 1977, signed by the [[Department of Defense]] [[General Counsel]], [[Deanne C. Siemer]], the Office of General Counsel reported on a search of Army, Navy and Air Force records from 1950 to the present, conducted from August 15 to September 15, 1977 at the request of the Secretary after the [[Director of Central Intelligence]], [[Stansfield Turner]], testified on August 3, 1977 to a joint session of the [[Senate Select Committee on Intelligence]] and the Senate Subcommittee on Health and Scientific Research that documents had been found on drug experiments on human subjects. The memorandum lists the codewords as the Director described them: MKSEARCH, MKOFTEN and MKCHICKWIT as projects with Defense Department contact, and MKULTRA, MKDELTA and [[MKNAOMI]] as primarily CIA projects. It dates MKDELTA to October 1952, MKULTRA to April 1953 and the late 1960s, MKNAOMI to the 1950s through 1969 for biological projects, and MKSEARCH to 1965 through 1973, with MKCHICKWIT ("to identify new drug developments in Europe and Asia and to obtain information and samples") and MKOFTEN ("to test the behavioral and toxicological effects of certain drugs on animals and humans") described as parts of MKSEARCH. It states that the three codeword projects were "planned, directed and controlled by the [[Central Intelligence Agency]]."[^2]
The memorandum reports three Army programs from 1969 to 1973, five Navy programs from 1947 to 1973 and none in the Air Force; in four of the eight, Defense Department participation "was limited to channeling funds to outside contractors in order that the sponsorship of the Central Intelligence Agency be covered." Army and Navy investigators began searching boxes of CIA financial records marked OFTEN and CHICKWIT on August 4, 1977, and on September 7 were allowed to search additional boxes of MKULTRA records.[^2]
The Army programs, all at or through [[Edgewood Arsenal]] Research Laboratories, were the identification of new drugs with behavioral effects (1967 to 1973, carried out mainly by a contractor in California, funded jointly by the Army and the CIA, which supplied 12,084 dollars in 1967 and 5,000 dollars in 1969, with no testing on human subjects; part of MKCHICKWIT); the building of computer data bases on pharmacological products (about 1968 to 1971, with CIA transfers in 1968, 1970 and 1971; part of [[MKOFTEN]]); and the determination of clinical effects of a glycolate-class chemical (1971 to 1973, funded by the CIA; part of MKOFTEN). In the third, Edgewood had tested a compound designated EA 3167 on animals, on human volunteers at [[Holmesburg Prison]] in [[Philadelphia]] using prisoners and at Edgewood using military personnel; the CIA reviewed the work in 1971 and transferred 37,000 dollars to Edgewood for further testing, mostly on animals, including whether the compound could be applied through the skin on adhesive tape, and the documents record one human experiment in June 1973 in which two military volunteers "were apparently tested." The Army document list (Appendix A, nine items) includes a 1966 annual report to the Edgewood Medical Research Laboratory from Duhring Laboratories of the [[University of Pennsylvania]] and an August 1975 note from Colonel McClure, Director of Biomedical at Edgewood, to Ed Owens on "Agent 3167."[^2] Deanne C. Siemer, General Counsel of the Department of Defense, told the Senate on September 20, 1977 that the testing of EA 3167 at Holmesburg "may have involved from 5 to 12 prisoners; one document says 5, another one says 12."[^3] The Army's list of Edgewood volunteer contracts for 1965 to 1975, placed before the Senate in 1975, shows prisoners at Holmesburg as the volunteers under three contracts: one with the University of Pennsylvania (April 1, 1964 to March 31, 1967) and two with [[Ivy Research Laboratories]] (June 28, 1968 to December 1, 1969, and a second ending September 30, 1971).[^4]
The five Navy programs, run through the [[Office of Naval Research]] as a funds conduit in most cases, were the synthesis of analogs of central nervous system stimulants (1971 to January 1973, a contractor in Massachusetts, with up to 117,938 dollars from the CIA between February 26, 1971 and June 23, 1972; the CIA authorization stated that funding through ONR "protects the Agency's association with this area of research and provides the contractor with credible sponsorship"); a search for a nonaddictive substitute for codeine (1954 to at least 1964, at the Addiction Research Center of the [[United States Public Health Service]] Hospital in [[Lexington, Kentucky]], with at least 282,215 dollars from the CIA and about 800 compounds tested on addicted patients); a study of the effects of blast concussion (October 1954 to December 1955, a contractor in California, 20,000 dollars from the CIA, after which the work became MKULTRA subproject 54 on the CIA's decision that "human experiments of a type not easily justifiable on medical-therapeutic grounds" were expected); the administration of LSD to human subjects (1952 to about 1956, a researcher in New York, MKULTRA subprojects 7, 27 and 40, with the Navy named as sponsor in one later CIA document that is not otherwise corroborated); and the development of speech-inducing drugs (1947 to 1953, funded by the Navy through the Naval Medical Research Institute, a New York contractor under the cover of a motion-sickness study, with the CIA records in the BLUEBIRD and [[Project Bluebird and Project Artichoke|ARTICHOKE]] files). The last item includes the memorandum's account that in August 1952 the [[Office of Naval Intelligence]] told the CIA that it had drugs it was about to test on human subjects "who would be unaware," that about eight Soviet defectors received them in Europe in September 1952, and that the tests were not satisfactory because the drugs tasted too bitter to conceal. The Navy document list (Appendix B) has 42 items, among them a May 15, 1957 report of Gross Research Laboratories, Inc., "On the Impact Thresholds of Brain Concussion," and records of the [[University of Rochester]] motion-sickness studies of 1951 to 1953.[^2]
The memorandum concludes that no Defense Department component or contractor then maintained a drug-testing program on human subjects in which the CIA was involved.[^2]
### Footnotes
[^1]: John D. Marks, *The Search for the Manchurian Candidate*, Chapter 12.
[^2]: General Counsel of the Department of Defense (signed by Deanne C. Siemer), memorandum for the Secretary of Defense, "Experimentation Programs Conducted by the Department of Defense That Had CIA Sponsorship or Participation and That Involved the Administration to Human Subjects of Drugs Intended for Mind-control or Behavior-modification Purposes," September 20, 1977, with Appendices A and B (Army and Navy document lists) and C (CIA documents), 17 pages, release file 02-A-0846, supplied by the vault owner and read on October 3, 2026 (text layer, first and last memorandum pages by image; names in the typed text are as the scan reads, some with OCR damage).
[^3]: Statement of Deanne C. Siemer, General Counsel, Department of Defense, *Human Drug Testing by the CIA, 1977*, hearings before the Subcommittee on Health and Scientific Research of the Committee on Human Resources, United States Senate, 95th Cong., 1st sess., September 20 and 21, 1977 (testimony of September 20), https://archive.org/details/human-drug-testing-by-the-cia-1977.
[^4]: *Biomedical and Behavioral Research, 1975*, joint hearings before the Subcommittee on Health of the Committee on Labor and Public Welfare and the Subcommittee on Administrative Practice and Procedure of the Committee on the Judiciary, United States Senate, 94th Cong., 1st sess., September 10, 12 and November 7, 1975, the Army list of "Research Contracts from Edgewood Arsenal Involving Drug Testing Volunteers, 1965-75," https://archive.org/details/US-Government-Medical-Experimentation-On-Humans.